Ovomet® (Eggshell Membrane) 500 mg 🇪🇸 Spain

Knee stiffness improved up to 26.6% by day 60 (RCT, 500 mg/day)

What it is

Ovomet® is whole eggshell membrane, the paper-thin layer found just inside an eggshell between the shell and the egg white. It is made in Spain by Eggnovo using only water and mechanical force, with no chemicals, which keeps its natural matrix intact. That matrix carries the same building blocks your joint cartilage is made of, including collagen, elastin, hyaluronic acid, and glucosamine, already assembled together rather than added one by one. MoveOn uses a 500 mg daily dose.

How it works

Eggshell membrane works on two fronts at once. First, it delivers the literal raw materials of cartilage, collagen, elastin, hyaluronic acid, and glucosamine, in the ready-made matrix your body already recognizes, so the supplies are on hand. Second, it acts as a signal inside the joint, helping switch on cartilage-building genes while quieting the enzymes and inflammatory pathways that break cartilage down. You can see this shift in the blood: in clinical trials it lowered CTX-II, a marker of cartilage breakdown, by 17.2% within the first week. The result is both the parts and the green light your body needs to maintain and rebuild joint tissue.

For your joints

This is the core of what MoveOn is for. In controlled trials, a single 500 mg dose a day eased knee osteoarthritis pain and improved stiffness by up to 26.6% by day 60, and in active adults it cut exercise-related joint pain within a day and stiffness within five days. Because it lowers the CTX-II cartilage-breakdown marker, it is not only soothing the joint but slowing the wear itself, giving your cartilage room to recover.

Beyond the joint

Beyond the knee, eggshell membrane supports connective tissue throughout the body. The same collagen, elastin, and hyaluronic acid it supplies are the building blocks of skin, tendons, and ligaments, so it backs the structures that keep you moving and resilient overall. Its calming effect on cartilage-breakdown enzymes reflects a broader steadying of the inflammatory pathways tied to everyday wear, and faster recovery from exercise-related stiffness means it helps you stay active, which feeds whole-body health.

Features

  • Patented whole eggshell membrane (Ovomet®)
  • Made in Spain by Eggnovo using only water and force, no chemicals
  • One ready-made matrix of collagen, elastin, hyaluronic acid, and glucosamine
  • 500 mg clinically studied daily dose
  • Backed by multiple human RCTs
  • Lowers the CTX-II cartilage-breakdown marker

The clinical evidence

RCT · 67 people · 60 daysOne 500 mg dose a day eased knee osteoarthritis pain (15.9% better than placebo by day 10) and stiffness (up to 26.6% by day 60), with more patients meeting OMERACT-OARSI response criteria.Ruff et al., 2009, Clinical Rheumatology. PMID 19340512.
RCT · 60 people · 1 week500 mg a day lowered the cartilage-breakdown marker CTX-II by 17.2% in the first week (and 9.9% at week 2) and sped recovery from exercise-related joint pain and stiffness.Ruff et al., 2018, Clinical Interventions in Aging. PMID 29497287.
RCT · 150 people · 12 weeks300 mg/day eggshell membrane significantly improved KOOS Pain and Daily Life function versus placebo, with benefit appearing within a week, peaking around week 3 and persisting to 12 weeks.Kiers & Bult, 2021, Journal of Medicinal Food. PMID 32633648.
RCT · 85 peopleIn healthy adults on an exercise regimen, 500 mg/day eggshell membrane rapidly improved exercise-induced joint pain (by day 1) and stiffness (by day 5) versus placebo, with a reduction in CTX-II cartilage turnover.Ruff et al., 2024, International Journal of Physical Medicine & Rehabilitation (non-PubMed-indexed).
Pilot · 18 people · 30 daysShort-term Ovomet eggshell membrane (300 mg/day) produced a significant decrease in joint pain from day 3 onward, falling about 52% by day 30 while placebo showed no significant change.Gil-Quintana et al., 2018, Journal of Osteoporosis and Physical Activity (non-PubMed-indexed).